The essential feature in establishing confidence in the quality and safety of allografts is the manufacturing quality control system utilized. This volume describes approaches to good manufacturing control. The experience in a number of countries is discussed, giving the reader quick access to developments in Argentina, Finland, Indonesia, Scotland and France. A balance needs to be struck between the use of allografts and of bone substitutes, depending on the clinical condition and the availability of grafts in a particular situation. The subject areas covered - such as mandibular reconstruction, spinal surgery, surgery and reconstruction of bone tumours and acetabular revision - demonstrate the universality of this technique.