This is the fourth and final volume of a series on autoimmunity, and findings related to particular clinical manifestations are presented, particularly systemic lupus erythematosus, scleroderma, rheumatoid arthritis, Sjogren's syndrome, antiphospholipid antibodies, and infections and autoantibodies.

Part A presents new principles in autoimmunity and new diagnostic tools; Part B focuses on genetics and advances in treatment; and Part C begins the focus on the clinical venue.

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