Description - Nanoparticulate Delivery to Cancerous Lesions by Vittorio Cristini
This book will present the most recent advances in mathematical modeling of nanoparticulate delivery to cancerous lesions. Mathematical modeling and computer simulation of the delivery of therapeutic agents to cancerous lesions is outlined via a discussion of the essential issues, with particular attention to those involving biobarriers. Modeling of various components of drug delivery is carried out, such as tumoral hemodynamics, the covective and brownian diffusion of drug molecules and nanovector within the tumor microcirculation and tumor interstitium, cell resistance mechanisms, diffusion of drug molecules along nanochannels.
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An Introduction to Physical Oncology: How Mechanistic Mathematical Modeling Can Improve Cancer Therapy Outcomes
