While preparing the manuscript for the press, some trifling alterations and additions have been made; but in doing this my original in tention of regarding the subject in its practical bearings has been carefully adhered to. The contents are divided into three chapters, Which, more or less, correspond With the three Croonian Lectures. The chemical history of calculous disease has been noticed only so far as the patho logy of the subject absolutely requires. The ob servations relating to the formation of calculi have.

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