Description - Tyrosine Hydroxylase by Naoi
Tyrosine hydroxylase is the rate-limiting enzyme in the biosynthesis of catecholamines. Since the discovery of this enzyme by Dr Toshiharu Nagatsu, the enzyme has been intensively studied in relation to both its physiological function in the brain and brain disorders - especially, the successful application of L-DOPA therapy for Parkinson's disease suggests that this enzyme should have a primary role in the progress of this disease. As a tribute to Dr Toshiharu Nagatsu, this book presents an overview of research on the enzyme, tyrosine hydroxylase. It provides the latest results on functional and clinical aspects of the enzyme and provides an insight in how the enzymatic and biochemical study of the monooxygenase has led to the understanding of many diseases, such as Parkinson's disease, stress and emotional disorders. This book should be of interest to researchers in the fields of neurochemistry, molecular biology, psycho- and neuropharmacology, neurology and psychiatry.
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Milestones in Neurotoxicity and Neuroprotection: A Tribute to Professor Toshiharu Nagatsu
